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       首頁(yè) >> 資源庫 >> 中文 >> 專(zhuān)家人才
    
                
    

                
    專(zhuān)家人才
    

                
    
                    
    
                        
      
                            
    • 姓名： 郭琳
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    • 性別： 女
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    • 職稱(chēng)： 副研究員
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    • 學(xué)歷： 博士
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    • 電話(huà)： 020-32015291
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    • 傳真： 
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    • 電子郵件: guo_lin09@gibh.ac.cn
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    • 通訊地址 廣州市科學(xué)城開(kāi)源大道190號
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      研究領(lǐng)域：
      
                            
    • 1.    多能性建立與維持的分子機制

      2.    利用單細胞測序技術(shù)研究細胞命運決定
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      承擔科研項目情況：
      
                            
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      社會(huì )任職：
      
                            
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      獲獎及榮譽(yù)：
      
                            
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      代表論著(zhù)：
      
                            
    • 1.Chen, J.*, Guo, L.*, Zhang, L.*, Wu, H., Yang, J., Liu, H., Wang, X., Hu, X., Gu, T., Zhou, Z., Liu, J., Liu, J., Wu, H., Mao, S.Q., Mo, K., Li, Y., Lai, K., Qi, J., Yao, H., Pan, G., Xu, G.L., and Pei, D. Vitamin C modulates TET1 function during somatic cell reprogramming. Nat Genet, 2013. 45(12): 1504-1509. (*共同第一作者)
      

      2.Chen, Y.*, Guo, L.*, Chen, J.*, Zhao, X., Zhou, W., Zhang, C., Wang, J., Jin, L., Pei, D., and Zhang, F. Genome-wide CNV analysis in mouse induced pluripotent stem cells reveals dosage effect of pluripotent factors on genome integrity. BMC Genomics, 2014. 1579.
      

      3. 郭琳，陳捷凱，裴端卿，維生素C與表觀(guān)遺傳調控，科學(xué)通報，2014, 59 (28) :2833-2839
      

      4.Li, D.*, Liu, J.*, Yang, X.*, Zhou, C., Guo, J., Wu, C., Qin, Y., Guo, L., He, J., Yu, S., Liu, H., Wang, X., Wu, F., Kuang, J., Hutchins, A.P., Chen, J., and Pei, D. Chromatin Accessibility Dynamics during iPSC Reprogramming. Cell Stem Cell, 2017. 21(6): 819-833 e816.
      

      5.Chen, J.*, Liu, H.*, Liu, J., Qi, J., Wei, B., Yang, J., Liang, H., Chen, Y., Chen, J., Wu, Y., Guo, L., Zhu, J., Zhao, X., Peng, T., Zhang, Y., Chen, S., Li, X., Li, D., Wang, T., and Pei, D. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet, 2013. 45(1): 34-42.
      

      6.Chen, J.*, Liu, J.*, Chen, Y., Yang, J., Chen, J., Liu, H., Zhao, X., Mo, K., Song, H., Guo, L., Chu, S., Wang, D., Ding, K., and Pei, D. Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics. Cell Res, 2011. 21(6): 884-894.
      

       
      

       
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