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專(zhuān)家人才
- 姓名: 彭廣敦
- 性別: 男
- 職稱(chēng): 研究員
- 學(xué)歷:
- 電話(huà):
- 傳真:
- 電子郵件: peng_guangdun@gibh.ac.cn
- 通訊地址 廣州市科學(xué)城開(kāi)源大道190號
簡(jiǎn)歷:
研究領(lǐng)域:
承擔科研項目情況:
國際干細胞學(xué)會(huì )(ISSCR)會(huì )員
社會(huì )任職:
Sanofi-SIBS 2017 Distinguished Young Faculty????
ISSCR 2017 Poster Award and Travel Award??
國家級人才項目
獲獎及榮譽(yù):
2018-2024?
1.?????? Fan Y, Bian X, Meng X, Li L, Fu L, Zhang Y, Wang L, Zhang Y, Gao D, Guo X, Lammi MJ, Peng G* & Sun S* (2024) Unveiling inflammatory and prehypertrophic cell populations as key contributors to knee cartilage degeneration in osteoarthritis using multi-omics data integration. Ann Rheum Dis (IF:27)
2.?????? Qu F, Li W, Xu J, Zhang R, Ke J, Ren X, Meng X, Qin L, Zhang J, Lu F, Zhou X, Luo X, Zhang Z, Wang M, Wu G, Pei D, Chen J, Cui G*, Suo S*, Peng G* (2023) Three-dimensional molecular architecture of mouse organogenesis. Nat Commun, 14: 4599
3.?????? Jiang F, Zhou X, Qian Y, Zhu M, Wang L, Li Z, Shen Q, Wang M, Qu F, Cui G, Chen K, Peng G* (2023) Simultaneous profiling of spatial gene expression and chromatin accessibility during mouse brain development. Nat Methods, 20: 1048–1057
4.?????? Xu HJ, Yao Y, Yao F, Chen J, Li M, Yang X, Li S, Lu F, Hu P, He S*, Peng G*, Jing N* (2023) Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells. Cell Regen, 12: 15
5.?????? Meng X, Cui G, Peng G* (2023) Lung development and regeneration: newly defined cell types and progenitor status. Cell Regen, 12: 5
6.????? Chen C, Liao Y, Peng G* (2022) Connecting past and present: single-cell lineage tracing. Protein Cell
7.?????? Cui G, Feng S, Yan Y, Wang L, He X, Li X, Duan Y, Chen J, Tang K, Zheng P, Tam PPL, Si W*, Jing N*, Peng G* (2022) Spatial molecular anatomy of germ layers in the gastrulating cynomolgus monkey embryo. Cell Rep, 40: 111285
8.?????? Wen L, Li G, Huang T, Geng W, Pei H, Yang J, Zhu M, Zhang P, Hou R, Tian G, Su W, Chen J, Zhang D, Zhu P, Zhang W, Zhang X, Zhang N, Zhao Y, Cao X*, Peng G*, Ren X*, Jiang N*, Tian C*, Chen ZJ* (2022) Single-cell technologies: From research to application. Innovation (Camb), 3: 100342
9.????? Li Z, Peng G (2021) Spatial transcriptomics: new dimension of understanding biological complexity. Biophysics Reports, 7: 1–17
10.?? Xia Q, Cui G, Fan Y, Wang X, Hu G, Wang L, Luo X, Yang L, Cai Q, Xu K, Guo W, Gao M, Li Y, Wu J, Li W, Chen J, Qi H, Peng G*, Yao H* (2021) RNA helicase DDX5 acts as a critical regulator for survival of neonatal mouse gonocytes. Cell Prolif, 54: e13000
11.?? Lin J, Wu S, Shen Q, Liu J, Huang S, Peng G*, Qiao Y* (2021) Base editing-mediated perturbation of endogenous PKM1/2 splicing facilitates isoform-specific functional analysis in vitro and in vivo. Cell Prolif, e13096
12.??? Peng, G.*, Cui, G., Ke, J. and Jing, N. (2020) Using Single-Cell and Spatial Transcriptomes to Understand Stem Cell Lineage Specification During Early Embryo Development. Annu Rev Genomics Hum Genet 2020; 21 163-181.
13.??? Peng G#*, Suo S#, Cui G#, Yu F#, Wang R, Chen J, Chen S, Liu Z, Chen G, Qian Y, Tam PPL, Han JJ*, Jing N* (2019) Molecular architecture of lineage allocation and tissue organization in early mouse embryo. Nature, 572: 528–532
14.??? Liu Q, Liu K, Cui G, Huang X, Yao S, Guo W, Qin Z, Li Y, Yang R, Pu W, Zhang L, He L, Zhao H, Yu W, Tang M, Tian X, Cai D, Nie Y, Hu S, Ren T, Qiao Z, Huang H, Zeng YA, Jing N, Peng G*, Ji H*, Zhou B* (2019) Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction. Nat Genet, 51: 728–738
15.??? Cui, G., Jing, N. and Peng, G.* (2019) Comments on ‘Molecular architecture of lineage allocation and tissue organization in early mouse embryo’. J Mol Cell Biol 11, 1024-1025.
16.??? Peng G, Han JJ (2018) Regulatory network characterization in development: challenges and opportunities. F1000Res, 7:
17.??? Cui G, Suo S, Wang R, Qian Y, Han JJ*, Peng G*, Tam PPL*, Jing N* (2018) Mouse gastrulation: Attributes of transcription factor regulatory network for epiblast patterning. Dev Growth Differ, 60: 463–472
18.??? Han X#, Luo S#, Peng G#, Lu JY, Cui G, Liu L, Yan P, Yin Y, Liu W, Wang R, Zhang J, Ai S, Chang Z, Na J, He A, Jing N, Shen X (2018) Mouse knockout models reveal largely dispensable but context-dependent functions of lncRNAs during development. J Mol Cell Biol, 10: 175–178??
2016-2018?
19.??? Peng G (2017) Looking Back: Single-Cell Analysis Empowering Stem Cell Studies (2017) Cell Stem Cell 20: 758 (Commentary)
20.??? Peng G, Tam PPL, Jing N (2017) Lineage specification of early embryos and embryonic stem cells at the dawn of enabling technologies. National Science Review, 4: 533–542
21.??? Peng G*, Jing N* (2017) The genome-wide molecular regulation of mouse gastrulation embryo. Sci China Life Sci, 60: 363–369
22.??? Chen J#, Suo S#, Tam PP, Han JJ, Peng G*, Jing N* (2017) Spatial transcriptomic analysis of cryosectioned tissue samples with Geo-seq. Nat Protoc, 12: 566–580
23.??? Peng G#, Suo S#, Chen J#, Chen W, Liu C, Yu F, Wang R, Chen S, Sun N, Cui G, Song L, Tam PP, Han JD*, Jing N* (2016) Spatial transcriptome for the molecular annotation of lineage fates and cell identity in mid-gastrula mouse embryo. Dev Cell, 36: 681–697??
(*: corresponding author; #: first author)
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完整論文情況Google scholar: https://scholar.google.com/citations?user=s7XddBgAAAAJ