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    專(zhuān)家人才

    • 姓名: 陳奇
    • 性別: 男
    • 職稱(chēng): 研究員
    • 學(xué)歷: 博士
    • 電話(huà): 
    • 傳真: 
    • 電子郵件: chen_qi@gibh.ac.cn
    • 通訊地址 廣州市黃埔區開(kāi)源大道190號

      簡(jiǎn)歷:

    • 2003-2007 華東理工大學(xué) 學(xué)士

      2007-2013 中國科學(xué)院上海生命科學(xué)研究院 博士

      2013-2021 德國馬普分子生物醫學(xué)研究所及明斯特大學(xué)醫學(xué)院 博士后

      研究領(lǐng)域:

    • 1、造血干細胞與骨髓微環(huán)境相互作用

      2、血管在呼吸疾病與再生中的功能

      承擔科研項目情況:

      社會(huì )任職:

      獲獎及榮譽(yù):

    • 1、2019 馬普分子生物醫學(xué)所突出工作獎

      2、2019 德國干細胞協(xié)會(huì )年會(huì )墻報獎

      3、2016 Gordon Research Conference旅行獎

      4、2011 第七屆歐洲斑馬魚(yú)會(huì )議墻報獎

       

      國際學(xué)術(shù)大會(huì )口頭報告

      1、2018 Gordon Research Conference, Endothelial cell phenotypes in health and disease

      2、2018 EMBL Conference, Hematopoietic stem cells from the embryo to the aging organism

      3、2015 Dutch German joint meeting of the Molecular Cardiology

      4、2012 Kloster Seeon Angiogenesis meeting

       

       

      代表論著(zhù):

    • 1Qi Chen#, Yang Liu#, Hyun-Woo Jeong, Martin Stehling, Van Vuong Dinh, Bin Zhou, Ralf H. Adams. Apelin+ endothelial niche cells control hematopoiesis and mediate vascular regeneration after myeloablative injury. Cell Stem Cell, 2019 Dec 5;25(6):768-783.e6. doi: 10.1016/j.stem.2019.10.006. #Equal contribution 影響因子:24.633

      Cell Stem Cell專(zhuān)門(mén)評論文章: Mutualism in the Marrow 2019 Dec 5;25(6):731-733. doi: 10.1016/j.stem.2019.11.007.

      2Yang Liu#, Qi Chen#, Hyun-Woo Jeong, Dong Han, J?rg Fabian, Hannes Drexler, Martin Stehling, Hans R. Sch?ler, Ralf H. Adams. Dopamine signaling regulates hematopoietic stem and progenitor cell function. Blood, 2021 Nov 25;138(21):2051-2065. doi: 10.1182/blood.2020010419. 封面文章, Featured Article# Equal contribution  (影響因子: 23.629)

      Blood專(zhuān)門(mén)評論文章: Dopamine motivates stem cells for reward. Blood. 2021 Nov 25;138(21):2012-2014. doi: 10.1182/blood.2021013538 

      3Yang Liu#, Qi Chen#, Hyun-Woo Jeong#, Bong-Ihn Koh, Emma Watson, Cong Xu, Martin Stehling, Bin Zhou, Ralf H. Adams. A specialized bone marrow microenvironment for fetal haematopoiesis. Nature Communications, 2022, 13 (1327). https://doi.org/10.1038/s41467-022-28775-x  (影響因子: 14.919)

      4Qi Chen, Hui Zhang, Yang Liu, Dagmar Zeuschner, Monica Corada, Elisabetta Dejana, Bin Zhou and Ralf H. Adams. Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells. (2016) Nature Communications. 7:12422 doi: 10.1038/ncomms12422. (影響因子: 14.919,已被引123) 

      5Qi Chen#, Luan Jiang#, Chun Li, Dan Hu, Ji-wen Bu, David Cai, Jiu-lin Du.  Haemodynamics- Driven Developmental Pruning of Brain Vasculature in Zebrafish. (2012) PLoS Biology 10(8): e1001374. #Equal contribution (已被引125)

      Nature選為亮點(diǎn)論文Highlight in Neurodevelopment: Low flow blood vessel pruning. Nature (2012) 488(7413): 560.

      PLoS Biology專(zhuān)門(mén)評論文章 (2012) Pruning Brain Vasculature for Efficiency. PLoS Biol 10(8): e1001375

      6David Rohde, Katrien Vandoorne, I-Hsiu Lee, Jana Grune, Shuang Zhang, Cameron S. McAlpine, Maximilian J. Schloss, Ribhu Nayar, Gabriel Courties, Vanessa Frodermann, Gregory Wojtkiewicz, Lisa Honold, Qi Chen, Stephen Schmidt, Yoshiko Iwamoto, Yuan Sun, Sebastian Cremer, Friedrich F. Hoyer, Oriol Iborra-Egea, Christian Mu?oz-Guijosa, Fei Ji, Bin Zhou, Ralf H. Adams, Joshua D. Wythe, Juan Hidalgo, Hideto Watanabe, Yookyung Jung, Anja M. van der Laan, Jan J. Piek, Youmna Kfoury, Pauline A. Désogère, Claudio Vinegoni, Partha Dutta, Ruslan I. Sadreyev, Peter Caravan, Antoni Bayes-Genis, Peter Libby, David T. Scadden, Charles P. Lin, Kamila Naxerova, Filip K. Swirski & Matthias Nahrendorf. Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease. Nature Cardiovascular Research 2022, 1(28–44) (創(chuàng )刊號論文)

              Nature 專(zhuān)門(mén)評論文章: Cardiovascular diseases disrupt the bone-marrow niche. https://doi.org/10.1038/d41586-021-03550-y

              Nature Reviews Cardiology專(zhuān)門(mén)評論文章: Cardiovascular disease alters the bone marrow vasculature https://doi.org/10.1038/s41569-022-00671-3

      7Cong Xu, Van Vuong Dinh, Kai Kruse, Hyun-Woo Jeong, Emma C Watson, Susanne Adams, Frank Berkenfeld, Martin Stehling, Seyed Javad Rasouli, Rui Fan, Rui Chen, Ivan Bedzhov, Qi Chen, Katsuhiro Kato, Mara Elena Pitulescu, Ralf H Adams. Induction of osteogenesis by bone-targeted Notch activation. eLife, 2022, Feb 4;11:e60183. doi: 10.7554/eLife.60183.

      8Ting-ting Liu, Xu-fei Du, Bai-bing Zhang, Hua-xing Zi, Yong Yan, Jiang-an Yin, Han Hou, Shan- ye Gu, Qi Chen, Jiu-Lin Du. Piezo1-mediated Ca2+ activities regulate brain vascular pathfinding during development. (2020) Neuron doi.org/10.1016/j.neuron.2020.07.025 (影響因子: 17.173)

      9Yang Liu, Xiao-Hui Xu, Qi Chen, Tong Wang, Cai-Yun Deng, Bao-Liang Song, Jiu-Lin Du, Zhen- Ge Luo. Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development. (2013) Nature Communications. doi:10.1038/ncomms3005  (影響因子: 14.919)

      10Yu Zhang, Bing Xu, Qi Chen, Yong Yan, Jiu-lin Du, Xufei Du. Apoptosis of Endothelial Cells Contributes to Brain Vessel Pruning of Zebrafish During Development. (2018) Front. Mol. Neurosci. 11:222. doi: 10.3389/fnmol.2018.00222 (影響因子: 5.639)