亚洲免费女色在线,久久综合给合久久狠狠狠…,亚洲一区二区成人,免费人成网555www

       首頁(yè) >> 資源庫 >> 中文 >> 專(zhuān)家人才

    專(zhuān)家人才

    • 姓名: Robert Weinkove
    • 性別: 男
    • 職稱(chēng): 教授
    • 學(xué)歷: 博士
    • 電話(huà): 
    • 傳真: 
    • 電子郵件: rweinkove@malaghan.org.nz
    • 通訊地址 廣州市黃埔區開(kāi)源大道190號

      簡(jiǎn)歷:

    • 教育經(jīng)歷:

      1996年,劍橋大學(xué) 克萊爾學(xué)院,文學(xué)學(xué)士

      1999年,倫敦大學(xué) 倫敦國王學(xué)院,醫學(xué)學(xué)士和外科學(xué)士

      2010-2013年,奧塔哥大學(xué),醫學(xué)博士

      工作經(jīng)歷:

      2018-至今  馬拉格漢醫學(xué)研究中心 臨床主任

      2012-至今  首都和海岸區衛生局  血液學(xué)家顧問(wèn)

      2012-2018  馬拉格漢醫學(xué)研究中心 臨床研究員

      2011  倫敦蓋伊/圣托馬斯醫院  血液學(xué)登記員

      2007-2010  馬拉格漢醫學(xué)研究中心 臨床研究員

      2004-2007  倫敦蓋伊/圣托馬斯醫院  血液學(xué)登記員

      2003-2004  倫敦圣喬治醫院高級醫務(wù)官

      2003年 圣詹姆斯大學(xué)利茲醫院 重癥監護病房醫生

      2002  倫敦蓋伊/圣托馬斯醫院 醫務(wù)高級干事

      2001-2002  漢諾威醫學(xué)院 住院醫生

      1999-2000  倫敦蓋伊/圣托馬斯醫院  醫學(xué)與泌尿泌尿外科醫生

      1999  倫敦格林尼治地區醫院 外科主任

       

      研究領(lǐng)域:

    • 癌癥免疫治療的臨床研究、血液腫瘤(主要為B細胞白血病和淋巴瘤)的診斷和管理。

      承擔科研項目情況:

    • 1.       已完成了新西蘭健康協(xié)會(huì )HRC資助的一項可行性試驗一項對乙酰氨基酚在發(fā)熱性中性粒細胞減少癥作用的隨機安慰劑對照試驗,擔任HRC資助的1/2MELVAC試驗的臨床顧問(wèn),該試驗主要研究MIMR制造的自體細胞疫苗治療晚期黑色素瘤患者。

      2.       承擔了China-MWC項目:項目名稱(chēng):New methods to improve CAR T cell therapy for cancer(提升CAR T細胞抗腫瘤效果的新策略);項目負責人:Rachel Perret, Robert Weinkove,參與人:Peng Li(李鵬), Le Qin(秦樂(lè ),;資助金額:492946新幣;項目執行期:2021.09-2023.08。

      3.       與李鵬組聯(lián)合開(kāi)展了國家自然科學(xué)基金課題國際(地區)合作交流項目。項目名稱(chēng):含TLR共刺激結構域的嵌合抗原受體T細胞的優(yōu)化及其抗腫瘤機制研究(項目編號:81961128003),資助直接經(jīng)費300萬(wàn)元,執行期間2019.07.01-2022.06.31

      4.       與李鵬組聯(lián)合開(kāi)展了廣州市對外科技合作項目,項目名稱(chēng):研發(fā)新型靶向惡性腫瘤并逆轉腫瘤微環(huán)境的細胞免疫治療(項目編號:201907010042),資助經(jīng)費200萬(wàn)元,執行周期2019.04.01-2022.03.31。

      社會(huì )任職:

    • 2019 新西蘭衛生研究理事會(huì )生物醫學(xué)研究委員會(huì )成員

      2019 ENABLE試驗管理委員會(huì )主席

      2019 REDDS-2試驗數據安全檢測委員會(huì )主席

      獲獎及榮譽(yù):

    • 2019 新西蘭衛生研究理事會(huì ) 臨床醫生研究獎學(xué)金

      201810 榮獲馬拉格漢醫學(xué)研究中心臨床醫生研究獎學(xué)金

      201211 榮獲奧塔哥大學(xué)臨床研究博士獎

      代表論著(zhù):

    • 1.        Burn OK, Farrand K, Pritchard T, Draper S, Tang CW, Mooney AH, Schmidt AJ, Yang SH, Williams GM, Brimble MA, Kandasamy M, Marshall AJ, Clarke K, Painter GF, Hermans IF, Weinkove R. Glycolipid-peptide conjugate vaccines elicit CD8+ T-cell responses and prevent breast cancer metastasis. Clin Transl Immunology. 2022 Jul 3;11(7):e1401.

      2.        Jarvis EM, Collings S, Authier-Hall A, Dasyam N, Luey B, Nacey J, Painter GF, Delahunt B, Hermans IF, Weinkove R. Mucosal-Associated Invariant T (MAIT) Cell Dysfunction and PD-1 Expression in Prostate Cancer: Implications for Immunotherapy. Front Immunol. 2021 Oct 19;12:748741.

      3.        Weinkove R, George P, Ruka M, Haira TH, Giunti G. Chimeric antigen receptor T-cells in New Zealand: challenges and opportunities. N Z Med J. 2021 Sep 17;134(1542):96-108.

      4.        McQuilten ZK, Busija L, Seymour JF, Stanworth S, Wood EM, Kenealy M, Weinkove R; Australasian Leukaemia and Lymphoma Group (ALLG). Hemoglobin is a key determinant of quality of life before and during azacitidine-based therapy for myelodysplasia and low blast count acute myeloid leukemia. Leuk Lymphoma. 2022 Mar;63(3):676-683.

      5.        Weinkove R, McQuilten Z, Adler J, Agar M, Blyth E, Cheng A, Conyers R, Haeusler G, Hardie C, Jackson C, Lane S, Middlemiss T, Mollee P, Mulligan S, Ritchie D, Ruka M, Solomon B, Szer J, Thursky K, Wood E, Worth L, Yong M, Slavin M, Teh B. Managing haematology and oncology patients during the COVID-19 pandemic: interim consensus guidance. Med. J. Aust. 2020; 212: 481-9.

      6.        George P, Brown A & Weinkove R. B-cell prolymphocytic leukemia with a t(4;14) FGFR3/IGH translocation: response to ibrutinib. Pathology 2020; 52: 491 2.

      7.        Grasso G, Field CS, Tang C-W, Ferguson PM, Compton BJ, Anderson RJ, Painter GF, Weinkove R, Hermans IF, Berridge MV. Vaccines adjuvanted with an NKT cell agonist induce effective T-cell responses in models of CNS lymphoma. Immunotherapy 2020; 12: 395 406

      8.        Dasyam N, George P, Weinkove R. Chimeric antigen receptor T-cell therapies: Optimising the dose. Br J Clin Pharm 2020; 86: 1678 89

      9.        George P, Dasyam N, Giunti G, Mester B, Bauer E, Andrews B, Perera T, Ostapowicz T, Frampton C, Li P, Ritchie D, Bollard CM, Hermans IF, Weinkove R. Third-generation anti-CD19 chimeric antigen receptor T-cells incorporating a TLR2 domain for relapsed or refractory B-cell lymphoma: a phase I clinical trial protocol (ENABLE). BMJ Open 2020;10:e034629

      10.     Dickinson M, Weinkove R. Maintaining a fit T-cell compartment: lymphoma treatment sequencing in the era of CAR T-cell therapies. Int Med J 2019; 49: 1338.

      11.     Weinkove R, George P, Dasyam N, McLellan A. Selecting costimulatory domains for chimeric antigen rceptors: functional and clinical considerations. Clin Transl Immunology 2019; 8: e1049

      12.     Weinkove R, Bowden E, Wood C, Campion V, Carter J, Hall R, Weatherall M, Beasley R, Young P. A randomised controlled feasibility trial of paracetamol during febrile neutropenia in hemato-oncology patients. Leukemia & Lymphoma 2019; 60: 1540-7

      13.     Wheeler M, White G, Brockie S, Dickson M, Weinkove R. Flow cytometric analysis of mechanically disaggregated bone marrow trephine biopsies. Cytometry B Clin Cytom 2018; 27: 120-6.

      14.     Speir M, Authier-Hall A, Brooks CR, Farrand KJ, Compton BJ, Anderson RJ, Heiser A, Osmond TL, Tang CW, Berzofsky JA, Terabe M, Painter GF, Hermans IF, Weinkove R. Glycolipid-peptide conjugate vaccines enhance CD8+ T cell responses against human viral proteins. Sci Rep. 2017; 7: 14273.

      15.     Fischer K, Al-Sawaf O, Fink A, Dixon M, Bahlo J, Warburton S, Kipps TK, Weinkove R et al. Venetoclax and obinutuzumab in chronic lymphocytic leukemia. Blood 2017; 129: 2702-5.

      16.     Speir M, Hermans IH, Weinkove R. Engaging natural killer T cells as universal helpers for vaccination. Drugs 2017; 7: 1-15.

      17.     Lucas N, Humble M, Sim D, Balm M, Carter JM, Weinkove R. Temporal changes in neutropenic blood culture isolates and disease associations: a single centre series of 1139 episodes. Int Med J 2017; 47: 962-5.

      18.     Mo A, McQuilten Z, Wood E, Weinkove R. Red cell transfusion thresholds in myelodysplastic syndromes: A clinician survey to inform future clinical trials. Int Med J 2017; 47: 695-8.