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專(zhuān)家人才
- 姓名： 單永禮
- 性別： 男
- 職稱(chēng)： 副研究員
- 學(xué)歷： 博士
- 電話(huà)：
- 傳真：
- 電子郵件: shan_yongli@gibh.ac.cn
- 通訊地址 廣州市黃埔區開(kāi)源大道190號
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2008.09-2012.06 安徽大學(xué) 生物科學(xué) 學(xué)士
2012.09-2018.01 中國科學(xué)院廣州生物醫藥與健康研究院 細胞生物學(xué) 博士
2018.01-2018.08 中國科學(xué)院廣州生物醫藥與健康研究院 助理研究員
2018.09-2021.01 南方醫科大學(xué)南方醫院 博士后
2021.01 至今 中國科學(xué)院廣州生物醫藥與健康研究院 副研究員
簡(jiǎn)歷：
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1. 人多能干細胞干性維持與譜系分化的研究
2. 人胎盤(pán)發(fā)育及胎盤(pán)疾病建模研究。
研究領(lǐng)域：
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1. 國家自然科學(xué)基金面上項目（2022）
2. 國家自然科學(xué)基金青年項目（2018）
3. 中國博士后科學(xué)基金面上項目（2019）
4. 廣東省自然科學(xué)基金面上項目（2020）
5. 廣州市科技計劃項目科學(xué)研究計劃一般項目（2019）
承擔科研項目情況：
社會(huì )任職：
獲獎及榮譽(yù)：
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1. Wei Yanxing, Wang Tianyu, Ma Lishi, Zhang Yanqi, Zhao Yuan, Lye Kathryn, Xiao Lu, Chen Chunlin, Wang Zhijian, Ma Yanlin, Zhou Xiaohua, Sun Fei, Li Weili, Dunk Caroline, Li Siliang, Nagy Andras, Yu Yanhong, Pan Guangjin*, Lye J Stephen*, Shan Yongli*. Efficient Derivation of Human Trophoblast Stem Cells from Primed Pluripotent Stem Cells. Science Advances, 2021, 7: eabf4416.
2. Shan Yongli#, Zhang Yanqi#, Zhao Yuan#, Wang Tianyu, Zhang Jingyuan, Yao Jiao, Ma Ning, Liang Zechuan, Huang Wenhao, Huang Ke, Zhang Tian, Su Zhenghui, Chen Qianyu, Zhu Yanling, Wu Chuman, Zhou Tiancheng, Sun Wei, Wei Yanxing, Zhang Cong, Li Chenxu, Su Shuquan, Liao Baojian, Zhong Mei, Zhong Xiaofen, Nie Jinfu, Pei Duanqing, Pan Guangjin*. JMJD3 and UTX determine fidelity and lineage specification of human neural progenitor cells. Nature Communications, 2020, 11 (1): 382.
3. Shan Yongli#, Liang Zechuan#, Xing Qi, Zhang Tian, Wang Bo, Tian Shulan, Huang Wenhao, Zhang Yanqi, Yao Jiao, Zhu Yanling, Huang Ke, Liu Yujian, Wang Xiaoshan, Chen Qianyu, Zhang Jian, Shang Bizhi, Li Shengbiao, Shi Xi, Liao Baojian, Zhang Cong, Lai Keyu, Zhong Xiaofen, Shu Xiaodong, Wang Jinyong, Yao Hongjie, Chen Jiekai, Pei Duanqing and Pan Guangjin*. (2017). PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naive ESCs. Nature Communications 8: 672.
4. Wei Yanxing#, Xiao Lu#, Ma Lishi, Wang Zhijian, Huang Liping, Li Huiying, Pan Guangjin, Lye J. Stephen, Shan Yongli*. Protocol to derive human trophoblast stem cells directly from primed pluripotent stem cells. STAR Protocols, 2022, 3: 101638.
5. Long Bong#, Shan Yongli#, Sun Yanling#, Wang Tianyu, Li Xudong, Huang Ke, Zhang Wenwen, He Yi, Wen Ruijuan, Li Yuhang, Mai Yuchan, Feng Yashu, Zhang Tian, Kang Baoqiang, Zhang Cong, Zhu Yanling, Gu Jiaming, Liu Jiajun, Zhang Xiangzhong*, Pan Guangjin*. Vitamin C promotes anti-leukemia of DZNep in acute myeloid leukemia. Biochimica et Biophysica Acta - Molecular Basis of Disease, 2022, 1868: 166357.
6. Zhao Yuan#, Wang Tianyu#, Zhang Yanqi#, Shi Liang, Zhang Cong, Zhang Jingyuan, Yao Jiao, Chen Qianyu, Zhong Xiaofen, Wei Yanxing, Shan Yongli*, Pan Guangjin*. Coordination of EZH2 and SOX2 specifies human neural fate decision. Cell Regeneration, 2021, 10: 30.
7. Xiao Lu#, Ma Lishi#, Wang Zhijian, Yu Yanhong, Lye J. Stephen, Shan Yongli*, Wei Yanxing*. Deciphering a distinct regulatory network of TEAD4, CDX2 and GATA3 in humans for trophoblast transition from embryonic stem cells. Biochimica et Biophysica Acta - Molecular Cell Research, 2020, 1867: 118736.
8. Ma Ning#, Shan Yongli#, Liao Baojian#, Kong Guanyi#, Wang Cheng, Huang Ke, Zhang Hui, Cai Xiujuan, Chen Shubin, Pei Duanqing, Chen Nansheng*, Pan Guangjin*. Factor-induced Reprogramming and Zinc Finger Nuclease-aided Gene Targeting Cause Different Genome Instability in beta-Thalassemia Induced Pluripotent Stem Cells (iPSCs). Journal of Biological Chemisrty, 2015, 290(19):12079-89.